I am taking a quick break from my usual theme of biomedical technology to post this very well written article on the Fermi Paradox.
In short the Fermi Paradox asks the following, "If there are give or take 100 billion stars in our galaxy and give or take 100 billion galaxies in the universe, there are a lot of opportunities for alien life to exist somewhere out there. If that's the case, why haven't we seen them??"
I personally think that there is nothing as humbling as looking out toward the night sky and knowing that there are perhaps species out there that are at least a billion years more technologically advanced than us. In that time a species could easily have colonized an entire galaxy! The intellectual difference between us and a species like that would be fare greater than between us and a hive of ants living in an anthill.
It's quite possible that the stars out there are teaming with life. If that's true, here's to hoping that they are friendly!
Some people stick with the traditional, feeling struck by the epic beauty or blown away by the insane scale of the universe. Personally, I go for the old “existential meltdown followed by acting weird for the next half hour.” But everyone feels something.